Cowboys vs. Titans Odds, Spread, Preview: NFL Week 17 Predictions

Cowboys vs. Titans Week 17 matchup preview and current betting lines

The Dallas Cowboys (11-4) are coming off a big win against the Philadelphia Eagles last week. Dak Prescott had one of the best games of his career after he completed all 24 passes against zone coverage (source: Next Gen Stats) on his way to leading Dallas to 40 points against a highly-ranked defense. Prescott threw another pick-six but was able to overcome it with a great performance, including the first time a quarterback has converted a third-and-30 in a close fourth quarter since at least 1994.

The Tennessee Titans (7-8) have lost five games in a row after blowing a fourth-quarter lead to the Houston Texans of all teams. It was the first fourth-quarter comeback win for Davis Mills in his career as backup Malik Willis threw two late interceptions for the desperate Titans.

But Houston also gave Dallas plenty of trouble as a 17.5-point underdog just a few weeks ago. Dallas is a heavy favorite again in this matchup thanks to the Titans’ recent slide and the fact that they are apparently resting many players to keep them healthy for the Week 18 rematch with Jacksonville to decide the AFC South. Running back Derrick Henry is also listed as doubtful, an injury designation that usually always means the player will not play that week, and this is a short week as it is the final Thursday night game of the 2022 NFL season.

The NFL Week 17 odds have the Cowboys as a 12-point road favorite with a total of 40 points.

Players to watch in the Cowboys vs. Titans game

Dallas Cowboys

Ezekiel Elliott: With Tony Pollard not practicing this week due to a thigh injury, it could very well be the Ezekiel Elliott show for Dallas like the old days. Zeke has scored a touchdown in eight straight games, and chances are he will add on to that streak in this matchup with the way the Titans have struggled with defensive starters the last month. Now imagine a defense filled with backups.

Tennessee Titans

Treylon Burks: Trying to name some of these Titans will be a challenge given who is out, but Burks has been a solid rookie who can make plays in the passing game. He just won’t let anyone forget about A.J. Brown, the receiver the team traded on draft day before taking Burks in the first round. But with Malik Willis struggling to throw for 100 yards in any of his three starts, it will be tough for Burks to shine in this matchup.

Cowboys vs. Titans prediction

Our Best NFL Bets for the Cowboys vs. Titans game

We have two NFL Week 17 predictions for this final Thursday night game of the season.

Cowboys vs. Titans Point Spread Pick: Cowboys -11 (-120)

The Cowboys vs. Titans spread opened with the Cowboys as a 9.5-point road favorite. It has only continued to go up as we find out more about which Titans are inactive. Most sportsbooks are showing the Cowboys as an 11 or 12-point favorite, and some are even up to 12.5. But you can get the Cowboys at -11 at BetMGM.

The game really is a mismatch with Dallas’ ability to score a ton of points while the Titans are likely going to be without Ryan Tannehill and Derrick Henry. When you remove those elements, what is really left to this offense? Julius Chestnut is expected to get a lot of carries, and no one even knows who he is. I could have made him up and most wouldn’t have realized it.

The Cowboys are going to slice and dice through a Tennessee defense that could be without as many as 10 starters. The only question about the spread is if the Cowboys get bored and call off the dogs early, and maybe the Titans get a backdoor cover in garbage time. The Cowboys coughing the ball up with a few turnovers and keeping it close is always a possibility too.

Remember, this Dallas team was a Jeff Driskel goal-line run from going down 30-20 to the 1-win Texans a few weeks ago. But after the big win over the Eagles, and the lack of talent the struggling Titans are putting on the field, do not overthink this one. The Cowboys are going to win by at least two touchdowns in your NFL bet of the week.

Remember to read our NFL picks page for more betting tips.

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Cowboys Total: Over 27 Points (+110)

Technically, the Titans have only allowed more than 22 points in three games this season: Buffalo (41), Philadelphia (35), and Jacksonville (36). Those last two were back to back and recent, and we know the Cowboys are one of the best scoring teams in the league since Dak Prescott returned.

Dallas has scored at least 27 points in eight games this year, including four games with 40 points. Since Prescott returned in Week 7, the Cowboys have scored at least 24 points in every game.

Again, this figures to be a poor Tennessee lineup with the following defensive starters already ruled out: Jeffery Simmons, Bud Dupree, Zach Cunningham, Dylan Cole, and Amani Hooker. Corner Kristian Fulton and lineman Denico Autry are also doubtful to play.

It would be a big upset if the Cowboys did not score 30 points in this game, but we’ll settle for over 27 at a good price.

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Frequently asked questions about the Cowboys vs. Titans game in Week 17

The game is being played at Nissan Stadium in Nashville, Tennessee.

Since 2018 under Mike Vrabel, the Titans are a respectable 9-5 ATS as a home underdog. But this is new territory for Vrabel as an underdog of two touchdowns at home.

Since 2020, McCarthy in Dallas is 7-3 ATS as a road favorite, which is tied with Cincinnati for the best record in the league in that time (min. two games). As a favorite in general since 2020, the Cowboys are 17-14 ATS, which is the fourth-best record in the league.

You can find them at our player prop picks and daily NFL predictions.